I launch a new Amazon Linux 2 AMI t2 micro instance in N.Virginia with all default settings (next, next, next, next...) and once up and running, I ssh into it, and no connectivity to the Internet.
I do the same in Ohio, and I have Internet connectivity (ping, traceroute, yum, etc.).
I've been comparing the VPC, IGW, Network ACL, Route Table, Subnets... no differences (other than N.Virginia has 6 subnets and Ohio 3). I wouldn't expect there would be differences as I use all defaults when launching.
N.Virginia instance does have DNS resolution, but again no connectivity.
Both are using an identical security group that has HTTP(80), SSH(22) and ICMP open inbound to all IPv4 addresses, and no outbound rules.